What are the symptoms of serum sickness?
Symptoms of serum sickness can include:Fever.General ill feeling.Hives.Itching.Joint pain.Rash.Swollen lymph nodes..
How long does serum sickness reaction last?
Serum sickness usually improves in 7 to 10 days, with full recovery in 2 to 4 weeks. However, it may lead to nervous system disorders and a life-threatening allergic reaction called anaphylaxis, so it is important to get medical treatment.
Is serum sickness serious?
While it can cause serious symptoms, serum sickness typically goes away on its own within a week to six weeks. If you’ve recently taken medication containing nonhuman proteins and are having symptoms, contact your doctor as soon as possible.
What is acute serum sickness?
Serum sickness is an immune-complex-mediated hypersensitivity reaction that classically presents with fever, rash, polyarthritis or polyarthralgias. It was first recognized as an entity in the early 1900s in patients who had received heterologous antisera, which was historically used to treat infectious diseases.
How do you test for serum sickness?
The following studies are indicated in patients with serum sickness:CBC with differential – Leukocytosis or leukopenia, eosinophilia, or mild thrombocytopenia.Erythrocyte sedimentation rate and C-reactive protein levels – Usually slightly elevated.Urinalysis – Proteinuria, hematuria, active sediment.More items…•
How do you get serum sickness?
Serum sickness is an immune response that’s similar to an allergic reaction. It happens when antigens (substances that trigger an immune response) in certain medications and antiserums cause your immune system to react. The antigens involved in serum sickness are proteins from nonhuman sources — usually animals.